Redmi Note 10S has Android 11 based MIUI 12.5. Apart from this, it has a 6.43 inch Full HD Plus display, which has a resolution of 1080x2400 pixels. The display is AMOLED and has a brightness of 1,100 nits. There is protection of Gorilla Glass 3 on the display. The phone has a MediaTek Helio G95 processor, Mail-G76 MC4 GPU for graphics, LPDDR4X RAM up to 8 GB and 128 GB of storage.

It has four rear cameras in which the first lens is 64 megapixels, which has an aperture f / 1.79. The second lens is 8 megapixels ultra wide, the third lens is a 2 megapixel macro and the fourth lens is a 2 megapixel depth sensor. For selfie, it has a 13 megapixel camera.

For connectivity, it has 4G, Wi-Fi, GPS, Bluetooth, IR blaster, NFC, 3.5mm headphone jack and USB Type-C port and side mounted fingerprint sensor. It has a 5000mAh battery which supports 33W fast charging and will be found in the box along with the charger phone. The phone has an IP53 rating for waterproofing.